个人简介：王正旋，中共党员、博士、硕士生导师，云南省“三区”科技人才。本、硕、博毕业于哈尔滨工业大学，2022年获得工学博士学位。目前担任Journal of future food期刊青年编委和云南民族大学学报编委，发表SCI论文30余篇，其中第一作者或通讯共20篇，发明专利4项，承担云南省基金2项、云南省重点项目1项。

一、在研项目

1.基于莓茶PPARγ激活剂物质基础及多靶点降血脂作用机制研究，科技厅面上项目202401AT070353，10万元

2.基于Nrf2调控的紫米蛋白肽抗氧化作用机制研究，科技厅青年基金202301AU070041，5万元

3.云南高原牦牛乳调制乳粉研发，重大专项（生物种业和农产品精深加工），202502AE090039，50万元

4.DHM改善内皮细胞损伤作用效果及机制研究，校人培基金KKZ3202446087, 3万元 （结题）

5.2024年云南省三区科技人才-王正旋，KKEE202446025,云财教〔2023〕283号，2万元（结题）

二、发表论文情况

[1]Zhen, Li; Peng, Jianhong; Cui, Huimin; Tao, Junhong; Liu, Yaping; Cao, Jianxin; El-Seedi, Heshamr; Cheng, Guiguang*;Wang, Zhengxuan*, 2026. Rosa chinensis cv. ‘JinBian’ flowers alleviates brain damage and cognitive deficit by inhibiting ferroptosis via the Keap1/Nrf2/GPX4 pathway and regulating gut microbiota.Phytomedicine, 153, 157942.

[2]Sun, Long; Jia, Yiqing; Jiang, Min; Ye, Renfeng;Wang, Zhengxuan*; Cheng, Guiguang*; Liu, Yaping, 2025. Tailoring purple rice bran protein via multi-modal modifications: Chemical, physical, and enzymatic strategies for enhanced functionality.International Journal of Biological Macromolecules, 334, 149047.

[3]Su, Qinge; Hu, Junbo; Cui, Huimin; Zheng, Fangyuan; Liu, Yaping;Wang, Zhengxuan*; Cheng, Guiguang*, 2025. Effect of Ultra-High Pressure on the Extraction of the Free, Esterified, and Bound Phenolics from Dendrobium fimbriatum Hook: Chemical Constituents and Antioxidant Ability.Molecules, 30, 1836.

[4]Hu, Junbo; Li, Chunyan; Li, Yuansheng; Zhao, Zhenhao; Liu, Yaping; EI-Seedi, Hesham;Wang, Zhengxuan*; Cheng, Guiguang*, 2025. Innovative rice alcohol soluble protein-casein matrix for encapsulating purple rice bran anthocyanins: Enhanced digestive stability and bioaccessibility in Caco-2 cell monolayer model.International Journal of Biological Macromolecules, 331, 148518.

[5]Wang, Yongchao; Sun, Long; Peng, Jianhong;Wang, Zhengxuan*; Zhao, Tianrui; Cao, Jianxin; Liu, Yaping; Cheng, Guiguang*; Brennan, Charles, 2025. Chemical composition and functional properties of protein-polyphenol complexes from purple rice: Effects of alkaline and enzymatic extraction.Food Chemistry, 489, 145010.

[6]Zhao, Zhenhao; Hu, Junbo; Cui, Huimin; Zhao, Tianrui; Liu, Yaping;Wang, Zhengxuan*; Cheng, Guiguang*, 2025. Tyrosinase inhibition and enzyme kinetics of red rice bran protein peptides: Mechanism, identification, in silico exploration, and experimental validation.Food Bioscience, 67, 106319.

[7]Wang, Yongchao; Zhang, Jian; Zhao, Tianrui; Cao, Jianxin; Khan, Afsar;Wang, Zhengxuan*; Liu, Yaping*; Cheng, Guiguang*, 2024. Acute, subacute, and sub‐chronic toxicity evaluation of Bletilla formosana tubers in rats.Food safety and health (Melbourne, Victoria), 2, 117-132.

[8]Li, Chunyan; Li, Mengcheng; Zhao, Zhenhao; Khan, Afsar; Zhao, Tianrui; Liu, Yaping;Wang, Zhengxuan*; Cheng, Guiguang*, 2024. The influences of extraction methods on the chemical constituents of Lyonia ovalifolia (wall.) Drude and intracellular protective effects based on metabolomics analysis.Food Chemistry, 456, 140031.

[9]Wang, Yongchao; Wang, Yongpeng; Zhao, Tianrui; Li, Mengcheng; Wang, Yudan; Cao, Jianxin; Liu, Yaping;Wang, Zhengxuan*; Cheng, Guiguang*, 2024. Protective Effect of Que Zui Tea on d-Galactose-Induced Oxidative Stress Damage in Mice via Regulating SIRT1/Nrf2 Signaling Pathway.Molecules (Basel, Switzerland), 29, 1384.

[10]Zhao, Tianrui; Zheng, Fangyuan; Liu, Yaping; Khan, Afsar;Wang, Zhengxuan*; Cheng, Guiguang*, 2023. A Comparative Analysis of Chemical Constituents and Antioxidant Effects of Dendrobium fimbriatum Hook Fractions with Different Polarities. International Journal of Molecular Sciences, 24, pp 12646.

[11]Hu, Yiwen; Li, Mengcheng; Wang, Yongpeng; Xue, Qingwang; Luo, Xiaodong; Khan, Afsar; Zhao, Tianrui; Liu, Yaping;Wang, Zhengxuan*; Wang, Yudan*; Cheng, Guiguang*, 2023. Protective effect of hot-water and ethanol-aqueous extracts from Anneslea fragrans against acetaminophen-induced acute liver injury in mice.Food and Chemical Toxicology, 179, 113973.

[12]Wang, Zhengxuan; Sun, Pengzhen; Zhao, Tianrui; Cao, Jianxin; Liu, Yaping; Khan, Afsar; Zhou, Wenbing; Cheng, Guiguang, 2023. E Se tea extract ameliorates CCl4 induced liver fibrosis via regulating Nrf2/NF-κB/TGF-β1/Smad pathway.Phytomedicine, 115, 154854.

[13]Wang, Yudan; Deng, Xiaocui; Liu, Yaping; Wang, Yifen; Luo, Xiaodong; Zhao, Tianrui;Wang, Zhengxuan*; Cheng, Guiguang*, 2023. Protective effect of Anneslea fragrans ethanolic extract against CCl4-induced liver injury by inhibiting inflammatory response, oxidative stress and apoptosis.Food and Chemical Toxicology, 175, 113752.

[14]Wang, Zhengxuan; Liang, Mingcai; Liu, Bingxiao; Yang, Lin, 2022. Methionine strengthens anti-inflammation of rice protein via depressing NF-kappa B activation and stimulating Msr expression in rats fed cholesterol-enriched diets.FOOD SCIENCE AND BIOTECHNOLOGY, 31, 745-758.

[15]Wang, Zhengxuan; Liang, Mingcai; Li, Hui; Liu, Bingxiao; Yang, Lin, 2022. Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 47, 826-838.

[16]Zhengxuan Wang, Liang Cai, Hui Li, Mingcai Liang,Lin Yang*. Rice Protein Stimulates Endogenous Antioxidant Response Attributed to Methionine Availability in Growing Rats[J]. Journal of Food Biochemistry, 2020, 44:e13180.

[17]Zhengxuan Wang, Mingcai Liang, Hui Li, Liang Cai, Hongjuan He, Qiong Wu,Lin Yang*. L-Methionine Activates Nrf2-ARE Pathway to Induce Endogenous Antioxidant Activity for Depressing ROS-derived Oxidative Stress in Growing Rats[J]. Journal of the Science of Food and Agriculture, 2019, 99(10):4849-4862.

[18]Zhengxuan Wang,Mingcai Liang, Hui Li, Liang Cai,Lin Yang*. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway[J]. International Journal of Molecular Sciences, 2019, 24(20):6164.

[19]Zhengxuan Wang, Ye Liu, Hui Li, Lin Yang *. Rice proteins, extracted by alkali and α-amylase, differently affect in vitro antioxidant activity[J]. Food Chemistry, 2016, 206: 137-145.

[20]Zhengxuan Wang, Hui Li, Mingcai Liang,Lin Yang*. Glutelin and prolamin, different components of rice protein, exert differently in vitro antioxidant activities[J]. Journal of Cereal Science, 2016, 72: 108-116.

三、专利

1.王正旋;赵振豪;胡竣博;李院生;程桂广;刘亚平.一种红米米糠源小分子肽及其应用.授权号: CN 119684400 B, 2025年12月19日

2.王正旋,李春燕,肖珊珊,崔天琦,程桂广,刘亚平.一种紫米花色苷纳米微胶囊的制备方法.受理号: 202410682637, 2024年5月29日

3.王正旋,赵振豪,李颖姣,李浩南,肖珊珊.一种速溶普洱茶发酵装置及加工工艺.受理号: 2024101053777. 2024年1月25日

招生专业：食品科学与工程，生物与医药

电子邮箱：WZX@kmust.edu.cn