个人简介：刘亚平，教授/博导，昆明理工大学食品科学与工程学院教师。2012年毕业于中国科学院昆明植物研究所植物化学与西部植物资源可持续利用国家重点实验室，同年留在该国家重点实验室工作。于2020年11月调入昆明理工大学。至今共发表研究论文120余篇，其中SCI研究论文100余篇，包括第一作者和共通讯作者共发表研究论文56篇，其中SCI论文48篇，包括中科院JCR分区一区论文的8篇，中科院JCR分区二区的10篇；共同申请专利10项，10项获得授权，包括2项国际专利。主持国家及省部级项目10余项，包括国家自然科学基金面上项目、地区基金、青年基金、云南省重点研发计划、云南省高层次人才培养支持计划“青年拔尖人才”项目、以及云南省基础研究面上项目、云南省和昆工双一流建设面上项目。参与完成了国家自然科学基金杰出青年基金、联合基金、国家重大新药创新等项目的完成，作为主要完成人参与完后新药灯台叶总生物碱胶囊的I、II期临床研究以及成果转让。

主要研究项目：

1、主持的研究项目：

（1）国家自然科学基金地区基金“选择性抑制非小细胞肺癌的吲哚生物碱结构功能与作用机制”，2024.01-2027.12，项目编号为32360114，直接经费32万元，主持，在研。

（2）云南特色植物提取实验室平台建设专项，“云南省食品安全地方标准的制定—东紫苏”，2025.01-2026.12，项目编号为YKKF202401，资助经费30万元，主持，在研。

（3）云南省基础研究专项—面上项目“芒果非食用部位中抑制氧化应激活性物质和抗衰老作用机制研究”，2022.06-2025.05,项目编号为202101AT070436，资助经费10万，主持，结题。

（4）云南省昆明理工大学“双一流”创建联合专项“基于液质联用（UPLC-DAD-HRMS/MS）技术深入挖掘新颖的吲哚生物碱及其抗肿瘤活性研究”，2021.12 - 2024.11,项目编号为202101BE070001-053，资助经费20万，主持，结题。

（5）国家自然科学基金面上项目“马钱族中抗胶质瘤干细胞的吲哚生物碱结构与活性研究”，2019.1-2022.12，项目编号为31872676，直接经费60万元，主持，结题。

（6）云南省生物医药领域科技计划项目子课题，“食用玫瑰等6种云南特色药食同源植物的物质基础研究”，2019.1-2021.12，项目编号为2019ZF010，资助经费150万，主持，结题。

2、负责的科研平台、团队及人才项目：

（1）云南省高层次人才培养支持计划青年拔尖人才“基于新药启发的吲哚生物碱新颖结构及抗肿瘤干细胞活性研究”，2021.01-2025.12,资助经费50万，主持，在研。

（2）昆明理工大学高层次人才平台建设项目，2021.01-2028.12,资助经费80万，主持，在研。

3、承担的教学改革项目：

（1）2022年云南省专业学位案例库—《高等食品化学》案例库建设项目，2022.01-2024.12，资助经费3万元，主持，在研。

近期的代表性论文专利：

(1)Sun,L.;Jia,Y.Q.;Jiang,M.;Ye,R. F.;Wang, Z. X.*; Cheng, G. G.*;Liu, Y. P. *.Tailoring purple rice bran protein via multi-modal modifications: Chemicalphysical, and enzymatic strategies for enhanced functionality.International Journal of Biological Macromolecules2025,334,149047.

(2)Hu,Y. R.;Jia, Y.Q.;Li,Z. L.;Wang,Z. S.;Wei,T.;Bi,F. F.;Wang,Y. R.;Qin,Y. Y.;Afsar Khan,A.;Liu, Y. P. *;Cheng, G. G.*Impact of Different Proportions of Purple Rice and ChanterellesPowder on Physicochemical, Sensory, and Starch DigestibilityProperties in Wheat Bread.Foods2025,14,1343.

(3)Teng, S. F.; Li, F. R.; Cui, Q. M.; Khan, A.; He, T.; Luo, X. D.^*;Liu, Y. P.^*;Cheng, G. G.^*A review on the genus Melodinus: traditional uses, phytochemical diversity and pharmacological activities of indole alkaloidsPhytochemistry Review2025,24, 1143-1196.

(4)Chen, T. M.; Teng, S. F.;Yang, H. L.;Zhao, Y. L.; Zhang, J. X.;Liu, J. T.;ZhouW. B.*;Liu, Y. P. *;Cheng, G. G.*The investigation on an ethnic medicinal plant of Elsholtiza bodinieri Vaniot: chemical constituents, acute, 28-day subacute and 90-day subchronic toxicity evaluationJournal of Ethnopharmacology2024,335, 118635.

(5)Li, Y. Q.; Qiu, L. Y.; Wang, Y. F.; Wang, Z. X.;Cheng, G. G.*;Liu, Y. P. *.Phytochemicals from the rhizome of Bletilla formosana and their antioxidant, cytoprotective and anti-inflammatory activities.Food Bioscience2024, 60, 104339.

(6)Zhang, J. X.;Zhang, J K.; Wang, X. Q.;Chen, T. M.;Wang, Z. X.;Liu, Y. P. *;Cheng, G. G.*. Isolation and structural characterization of flavonoids from E Se tea and their synergistic inhibitory effects on lipid accumulation via regulating AMPK/ACC pathway.Food Bioscience2024, 60, 104517.

(7)Wang, Y. C.; Zhang, J.; Zhao, T. R.; Cao, J. X.; Khan, A.;Wang, Z. X.*;Liu, Y. P. *;Cheng, G. G.* Sub-Acute, subacute, and chronic toxicity evaluation ofBletilla formosanatubers in rats.Food Safety and Health2024, 2, 117-132.

(8)Zhang, X. Y.; Xue, Q. W.; Zhao, J. H.; Zhang, H. B.; Dong, J. H.; Cao, J. X.; Wang, Y. D.;Liu, Y. P. *;Cheng, G. G.* Chemical Constituents, Hypolipidemic, and Hypoglycemic Activities ofEdgeworthia gardneriFlowers.Plant Foods for Human Nutrition. 2024, 79, 440-450.

(9)Teng, S. F.; He, J. J.; Wang, X. Q.; Li, Y. Q.; Khan, A.;Zhao, T. R.;Wang, Y. D.;Cheng, G. G.*,Liu, Y. P. *A molecular networking-based isolation ofgardneria alkaloids fromGardneria distinctaand theiranti-inflammatory activity.Phytochemistry2023,209,113639.

(10)Zhang, J.; Chen, T. M.;Wang, Z. X.;Zhou, W. B.; Ullah, H.; Cao, J. X.;Liu, Y. P. *;Cheng, G. G.*The protective effect and mechanism of mangiferin on D-galactose-induced oxidative stress and cognitive impairment in aging mice by anintegrated network pharmacology and experimental validation strategyFood Frontiers,2023, 4, 1543-2096.

(11)Zhang, X. Y.; Li, M. C.; Zhen, L.; Wang, Y. D.; Wang, Y. F.; Qin, Y. Y.; Zhang, Z.H.; Zhao, T. R.; Cao, J. X.;Liu, Y. P. *;Cheng, G. G.*Ultra-High Hydrostatic Pressure Pretreatment on White Que Zui Tea: Chemical Constituents, Antioxidant, Cytoprotective, and Anti-Inflammatory ActivitiesFoods2023,12, 628.

(12)Zhao, J.-H.; Li, J.; Zhang, X.-Y.; Shi, S.; Wang, L.; Yuan, M.-L.;Liu, Y. P. *;Wang, Y.-D.*Confusoside fromAnneslea fragransAlleviates Acetaminophen-Induced Liver Injury in HepG2 via PI3K-CASP3 Signaling PathwayMolecules2023, 28, 1932.

(13)Yang, M.L.;Can Lu, C.; Fan, Z. F.;Zhao, T. R.;Cheng, G. G.;Wang, Y.-D.*, Cao, J. X.*;Liu, Y. P. *Hypoglycemic and hypolipidemic effects ofEpigynum auritumin high fat diet and streptozotocin-induced diabetic ratsJournal of ethnopharmacology,2022,288, 114986.

(14)Cheng C. S.; Gui, Q.-H.; Zhang, J.-K.; Tao, J.-H.; Zhao, T.-R.; Cao, J.-X.; Cheng, G.-G.; Lai, G.-F*.;Liu, Y. P. *Phenolic Constituents, Phenolic Constituents, Antioxidant and CytoprotectiveActivities, Enzyme Inhibition Abilities of Five Fractions fromVaccinium dunalianum Wight.Molecules2022, 27, 3432.

(15)Cui Q. M.; Cui X. Y.; Teng S. F.; He S. Y.;Liu, Y. P. *;Cheng, G. G.* Chemical constituents fromMelodinus axillarisW. T. Wang and their chemotaxonomic significance.Biochemical Systematics and Ecology.2022,105, 104530.

(16)Zhu, P. F.^#;Cheng, G.G.^#; Zhao, L.Q.; Khan, A.; Yang, X.W.; Zhang, B.-Y.; Li, M.C.;Liu, Y. P. *; Luo, X.-D. *.Antioxidant and Cytoprotective Effects of New Diarylheptanoids fromRhynchanthus beesianusJournal of Agriculture and Food Chemistry2021, 69, 6229-6239.

(17)Yuan, H. L.;^#Zhao, Y. L.^#, Qin, X. J.,Liu, Y. P. *,Yang, X. W. *; Luo, X. D*. Diverse isoquinolines with anti-inflammatory and analgesic bioactivities fromHypecoum erectumJournal of ethnopharmacology2021,270, 113811.

(18)Cheng, G.-G.^#;Liu, Y.-P.^#; Gu, J.; Qian, S.-Y.; Yang, H.-J.; Na, Z.-Y.; Luo, X.-D., Phytochemicals and Allelopathy of Induced Water Hyacinth against Microcystis aeruginosaJournal of Natural Products2021. 84, 1772-1779.

(19)Li, F. R.; Wang, Y. D.; He, S. Y.; K. A.; Xue, Q. W.; Cui, Q. M.; Liu. L.;Liu, Y. P.*;Cheng, G. G.*Targeted isolation of terpenoid indole alkaloids fromMelodinus cochinchinensis(Lour.) Merr. using molecular networking and their biological activitiesIndustrial Crops and Products2020, 157 112922.

(20)Zhu, P. F.; Zhao, Y. L.; Dai, Z.; Qin, X.J.; Yuan, H. L.; Jin Q.; Wang, Y. F.;Liu, Y. P.*Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum FruitsJournal of Agricultural Food Chemistry2020,68, 3079−3087.

(21)Yuan,H. L.^#;Zhao, Y. L.;^#Ding,C. F.;Zhu, P. F.;Jin, Q.;Liu, Y. P. *; Ding, Z. T.; Luo, X. D*.Anti-inflammatory and antinociceptive effects of Curcuma kwangsiensis and its bioactive terpenoids in vivo and in vitro.Journal of Ethnopharmacology.2020, 259, 112935,

(22)Xie, T. Z.; Zhao, Y. L.,He,J. J.; Zhao, L. X.; Wei, X.;Liu, Y. P. *; Luo, X. D*.Monoterpenoid indole alkaloids from the stemsofKopsia officinalis.Fitoterapia2020, 143, 104547.

招生专业：食品科学、生物与医药、农产品加工及贮藏

电子邮箱：liuyaping@kust.edu.cn